Cynaropicrin, A New Natural Approach To Suppress Skin Photoaging

Artichoke is a species of ‘thorny’ thistle originated in Mediterranean. On first encounter, this globular green monster may be somewhat off-putting, there are places around the world where people have neither tasted nor seen the Artichoke.

Artichoke, Mediterranean ‘Thorny’ Thistle

In past centuries the Artichoke was used as a diuretic. It was even thought to have deodorizing properties and was considered an ideal breath freshener.

Today, the Artichoke is being examined in research labs to explore its phytochemical contents. Two of these compounds, cynarin and silymarin are commonly known for its antioxidant and anti-inflammatory properties that may be beneficial in helping the liver to regenerate tissue growth.


Cynaropicrin, the less discussed phytochemical in Artichoke that is responsible for the typical bitter taste of Artichoke, provides remarked tolerance to pathogen, is found to exhibit antiaging of UV-induced skin by inhibiting the NF-κB activation.

It has been well established that the transcription factor NF-κB is activated in keratinocytes by Ultraviolet (UV) irradiation, and NF-κB is responsible for increased Matrix Metalloproteinase-1 (MMP-1) production in the dermis.

MMP-1: The major enzyme responsible for collagen 1 digestion


Numerous studies have shown Ultraviolet (UV) irradiation is one of the most harmful environmental factors that cause photoaging of the skin.

Aging of skin is characterized by skin wrinkling, laxity and pigmentation.


It has been recommended by experts to wear sunscreen when exposing to UV lights.

But according to Consumer Reports Consumer Reports, of more than 60 products tested, 23 were found to have less than half of the labeled SPF number.

More and more consumers are seeking for supplement that helps whitening and reduces pigmentation.

For years, Youth Hope has researched and worked on multiple approaches to develop innovative Whitening Skin Care Products and Whitening Supplement to meet the market demand for high quality whitening beauty products.

If you are interested, we are ready to present more extended information to you, and propose idea to incorporate in your new project launching.